Meet an Unreasonable Venture
Holobiome
Mapping the human microbiome to create the future of prebiotics and probiotics
Holobiome is a platform biotechnology company modifying the human microbiome with precision to optimize health and cure disease. Its foundation model maps how gut bacteria, biology, and diet interact, built on the world's most diverse collection of human gut bacteria, 3,000,000+ genomes, real-world data from 100,000+ people, and a 6,000-person ARPA-H-funded interventional trial. Holobiome turns these discoveries into consumer products and drugs, from a next-generation probiotic for depression to programs in pain, stress, and metabolic health.
Food & Water and Health
Notable Achievements
- Raised over $20M in venture financing, plus multiple corporate partnerships and grants.
- Won an ARPA-H award for a 6,000-person prebiotic trial, the largest microbiome study attempted.
- Assembled the world's most diverse and deeply profiled collection of human gut bacteria.
Currently Operating in Two Regions
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